Overview

Periarticular Multimodal Drug Injections in Total Knee Arthroplasty

Status:
Completed
Trial end date:
2009-04-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine whether periarticular multimodal drug injection (PMDI) would provide additional benefits in patients after total knee arthroplasty (TKA) for whom contemporary pain control protocols using the continuous femoral nerve block, intra-venous patient controlled analgesia (IV-PCA)and preemptive oral medications. We hypothesized that PMDI would reduce pain level and consumption of PCA and acute pain rescuer and would provide better functional recovery and patient satisfaction. We also hypothesized that the incidence of side effects and complications of the PMDI would be similar to the No-PMDI.
Phase:
Phase 4
Details
Lead Sponsor:
Seoul National University Hospital
Treatments:
Cefuroxime
Cefuroxime axetil
Epinephrine
Epinephryl borate
Ketorolac
Ketorolac Tromethamine
Morphine
Racepinephrine
Ropivacaine