Peri-Operative Lidocane, Ketamine, or Lidocane and Ketamine Combination, Infusion for Patients Undergoing Spine Surgery
Status:
Completed
Trial end date:
2013-01-01
Target enrollment:
Participant gender:
Summary
This study has been designed as a controlled clinical trial to evaluate the efficacy of brief
lidocaine infusion, brief ketamine infusion and a lidocaine/ketamine combined infusion when
added to conventional opioid therapy following major spine surgery, as well as to evaluate
the effects of the lidocaine/ketamine pain protocol on the feasibility of performing routine
intraoperative neurophysiology during spine surgery in adults and determine whether this
infusion protocol is compatible with intraoperative neurophysiology on spine surgery
patients. If one or more of the approaches is confirmed as efficacious and safe, it could
have a significant impact on the routine management of postoperative pain in this context.