Perfusion Imaging With Myocardial Contrast Echocardiography in HCM

• Status: Unknown status
• Trial end date: 2019-09-15
• Target enrollment: 0
• Participant gender: All

Summary

The objective of this study is to determine whether myocardial contrast echocardiography in patients with cardiomyopathy (HCM) can detect resting hypo-perfusion due to fibrosis or stress induced perfusion defects due to associated abnormalities in intramyocardial arteries and the microcirculation. A secondary aim will be to determine whether abnormalities in perfusion are associated with either severity of symptoms (chest pain and dyspnea), presence of arrhythmias, and regional function of the septum.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Oregon Health and Science University

Criteria

Inclusion Criteria:

• Age 18-80 years

• Established diagnosis of HCM

Exclusion Criteria:

• Known history of coronary or peripheral artery disease

• History of myocardial infarction

• Pregnant or lactating females

• Hypersensitivity to any ultrasound contrast agent

• Evidence right-to-left or bi-directional intracardiac shunt

• Moderate or greater valve disease other than from HCM (systolic anterior motion of the mitral valve)

• History of septal ablation or myectomy

• Hemodynamic instability

• Pacemaker dependent heart rhythm