Percutaneous Needle Fasciotomy +/- Corticosteroid Injection for Dupuytren's Contracture

• Status: Not yet recruiting
• Trial end date: 2029-12-01
• Target enrollment: 0
• Participant gender: All

Summary

Comparing percutaneous needle fasciotomy +/- corticosteroid injection for Dupuytren's contracture affecting metacarpophalangeal joints. A clinician-initiated, multicenter, randomized controlled trial.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Regionshospitalet Silkeborg

Criteria

Sufficient correction of MCP joint during the PNF treatment, defined as <20° passive extension deficit (PED), is a prerequisite for inclusion.

Inclusion Criteria:

• DC of ≥ 20° PED in MCP joint measured with a goniometer

• DC of either II-V finger

• Well-defined/palpable cord

Exclusion Criteria:

• Legally incapacitated

• Previous study inclusion with another finger ray

• Isolated PIP or DIP joint contracture, defined as MCP joint contracture < 20° PED regardless of the deficit in the PIP or DIP joint

• Previous hand surgery of the affected finger for any reason

• Known allergy to the study medication

• Anticoagulant therapy (Acetylsalicylic acid is NOT an exclusion criterion)

• Pregnant or lactation

• Insulin dependent diabetes mellitus

• Ongoing systemic infection or local infection at the site of the procedure

• Rheumatoid arthritis

• Amyloidosis or mycopolysaccharidosis

• Unable to communicate, cooperate or participate in follow-up