Overview

Pentoxifylline and Combination Antiretroviral Therapy to Improve Blood Vessel Function in HIV-Infected People

Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
People infected with HIV have a greater risk of developing cardiovascular disease than people not infected with HIV. This may be due to increased inflammation in the blood vessels. This study will determine whether an anti-inflammatory drug, pentoxifylline, in combination with antiretroviral medications, is more effective at improving blood vessel function and reducing inflammation than antiretroviral medications alone in people infected with HIV.
Phase:
Phase 2
Details
Lead Sponsor:
Indiana University
Collaborator:
National Heart, Lung, and Blood Institute (NHLBI)
Treatments:
Anti-Retroviral Agents
Pentoxifylline