Overview

Pemetrexed Plus Gemcitabine in Metastatic Breast Cancer Patients After Receiving Taxane Therapy

Status:
Completed
Trial end date:
2008-01-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of the study is to determine if the two drugs can help patients feel better while causing the tumor to become smaller or disappear; evaluate the safety of giving both pemetrexed and gemcitabine in patients with advanced breast cancer.
Phase:
Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Eli Lilly and Company
Treatments:
Gemcitabine
Pemetrexed
Taxane
Criteria
Inclusion Criteria:

- Must have received prior chemotherapy with Taxol (paclitaxel) or Taxotere (docetaxel).

- Less than 3 different chemotherapy treatments for metastatic disease.

- Prior treatment with hormonal and/or radiation therapy.

- Must have disease that can be measured.

- Must be able to take care of self needs for example personal hygiene

Exclusion Criteria:

- Must not be pregnant or breast-feeding.

- Cancer that has spread to the brain.

- Treatment with Gemcitabine or Pemetrexed

- Unable to take folic acid or Vitamin B12

- Treatment for another cancer within the last 5 years