Overview

Pembrolizumab, Lenvatinib and Chemotherapy After TKIs in NSCLC

Status:
Not yet recruiting
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
Adding chemotherapy or anti-VEGF to immunotherapy is an emerging strategy to enhance the efficacy of immunotherapy in many cancers. This phase 2 study aims to explore the preliminary efficacy of combination pembrolizumab with lenvatinib and chemotherapy in NSCLC patients with sensitizing EGFR, ALK, or ROS1 genetic aberration refractory to standard targeted therapy.
Phase:
Phase 2
Details
Lead Sponsor:
Dr Joanne CHIU
Treatments:
Carboplatin
Lenvatinib
Pembrolizumab
Pemetrexed