Overview

Pelvic Radiotherapy With Concurrent Neoadjuvant FOLFOX for Patients With Newly Diagnosed Rectal Adenocarcinoma

Status:
Terminated
Trial end date:
2018-10-05
Target enrollment:
Participant gender:
Summary
The purpose of this study is to assess the effects, both good and bad, of adding very low dose fractionated radiation therapy (LDFRT) to the pelvis, with FOLFOX chemotherapy prior to surgery. Standard pelvic radiation therapy given once a day (Monday through Friday) over approximately 5.5 weeks is not given in this study. You will receive 6 cycles of FOLFOX (each cycle is 2 weeks) and you will also get an LDFRT to your pelvis given twice a day on the first two days of each cycle.
Phase:
Phase 2
Details
Lead Sponsor:
University of Maryland
University of Maryland, Baltimore
Treatments:
Fluorouracil
Leucovorin
Oxaliplatin