Pegasys in Patients With Chronic Myeloid Leukemia (CML)
Status:
Terminated
Trial end date:
2014-03-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical research study is to learn if adding pegylated interferon-alfa 2a
(Pegasys) to the TKI that you are already receiving can help to control CML. The safety of
this treatment combination will also be studied.
Pegasys is a form of the drug interferon. It is designed to help the body's immune system to
fight infections. It may also affect the body's response to cancer.
A TKI (imatinib mesylate, nilotinib, or dasatinib) is designed to bind to and shut off a
protein in tumor cells called Bcr-Abl. Shutting Bcr-Abl off may prevent CML cells from
growing, and may cause them to die.
You are already receiving a TKI. This consent form will describe the administration of
Pegasys, any tests and procedures that need to be performed while you are receiving Pegasys,
and any risks/benefits there may be from receiving Pegasys.