Overview

Pediatric Tonsillectomy Pain Reduction Study

Status:
Completed
Trial end date:
2009-11-01
Target enrollment:
Participant gender:
Summary
Tonsillectomy is associated with a significant decrease quality of life in children secondary to pain, which is worsened with swallowing. The objective of the current study is to conduct a prospective, double-blind, placebo-controlled, randomized clinical trial using a pre-tonsillectomy infiltration of the tonsillar fossa comparing three treatment regimens in reducing post-tonsillectomy morbidity (i.e. pain, poor oral intake): 1) Placebo (saline injection) 2) bupivacaine (0.5%) + lidocaine (1%), 3) bupivacaine (0.5%) + lidocaine (1%) + clonidine (25 µg).
Phase:
Phase 3
Details
Lead Sponsor:
Vanderbilt University Medical Center
Treatments:
Anesthetics
Bupivacaine
Clonidine
Lidocaine