Pediatric Pain Optimization After Tonsillectomy

• Status: Not yet recruiting
• Trial end date: 2024-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare the use of short acting opioids (fentanyl/hydromorphone) with long acting opioids (methadone) for pain control following tonsillectomy surgery.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Duke University
• Treatments: Fentanyl; Hydromorphone; Methadone

Criteria

Inclusion Criteria:

1. Children ages 3 to 17 years old years

2. Presenting for elective tonsillectomy +/- adenoidectomy

3. Provide informed consent / assent (as appropriate)

Exclusion Criteria:

1. History of liver or kidney disease

2. Females with positive pregnancy test

3. Severe sleep apnea (Sleep study with Apnea Hypopnea Index (AHI) > 10)

4. Consistent daily opioid use for chronic pain ( >3 months)