Pediatric Ketamine Study for Pain Management

• Status: Terminated
• Trial end date: 2017-10-14
• Target enrollment: 0
• Participant gender: All

Summary

Direct comparison of intranasal sub-dissociative dose ketamine with intranasal fentanyl for the treatment of moderate to severe pain in pediatric patients in the emergency department.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Antonios Likourezos; Maimonides Medical Center
• Collaborator: Maimonides Medical Center
• Treatments: Fentanyl; Ketamine

Criteria

Inclusion Criteria:

• Children aged 3-17,

• weighing less than 50kg

• present to the pediatric ED with moderate-severe acute pain (defined as pain greater than or equal to 6/10).

• Treating physician determines the patient to require opioid analgesia.

Exclusion Criteria:

• Children with facial trauma or any abnormal nasal anatomy;

• developmentally delayed children;

• children with head trauma/increased intracranial pressure (ICP);

• children with known allergy to fentanyl or ketamine;

• children who are unable to provide pain scale assessment;

• children with chronic pain of greater than 4 weeks;

• Pregnant females;

• and children with a Glasgow Coma Scale (GCS)<15.