Pectoral Nerves Blocks for Chronic Pain

• Status: Unknown status
• Trial end date: 2019-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine whether pectoral nerves blocks（PECS） would reduce chronic pain at 3 months after modified radical mastectomy（MRM）surgery.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: First Affiliated Hospital Xi'an Jiaotong University
• Treatments: Ropivacaine

Criteria

Inclusion Criteria:

• Modified radical mastectomy

• American Society of Anesthesiologists physical status 1-3

• BMI 18-35 kg/m2

Exclusion Criteria:

• Declining to give written informed consent；

• Uncontrolled hypertension；

• Allergy to local anesthetics；

• Pregnancy；

• Alcohol or drug abuse；

• Prior breast surgery except for diagnostic biopsies；

• Contraindication to the use of regional anesthesia；

• History of chronic pain or psychiatric disorder and pregnant patients；

• Consumption of NSAID, cyclooxygenase-2 inhibitors or paracetamol within 24 hours before the investigation；

• Infection at the needle site.

• Inability to properly describe postoperative pain to investigators (eg, language barrier, neuropsychiatric disorder)