Pecto-Intercostal Fascial Block for Postoperative Analgesia After Cardiac Surgery

• Status: Completed
• Trial end date: 2019-11-27
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether administration of a pecto-intercostal fascial plane block (PIFB) with bupivacaine is a more effective therapy for postoperative analgesia after cardiac surgery as compared to patients who receive a sham block of normal saline.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Beth Israel Deaconess Medical Center
• Treatments: Bupivacaine

Criteria

Inclusion Criteria

• Patients 18 years of age or older

• Undergoing cardiac surgery with sternotomy, limited to CABG, CABG+valve surgeries and isolated valve surgeries.

Exclusion Criteria

• Current participation in another interventional study

• Preoperative LVEF < 30%

• Use of mechanical circulatory support

• Emergent procedures

• Aortic surgeries, transplants ventricular assist device insertions, bentall, or grafts

• Minimally invasive cardiac procedures or those with thoracotomy approach

• Patients receiving other modalities of regional anesthesia like intrathecal morphine

• Chronic opioid use for chronic pain conditions with tolerance (total daily dose of an opioid at or more than 30 mg morphine equivalent for more than one month within the past year)

• Current use of TCA, gabapentin, or pregabalin

• Hypersensitivity to bupivacaine

• Women who are pregnant or breastfeeding

• Non English speaking