Pectin Start Early Enteral Nutritional Support in Critically Ill Patients

• Status: Completed
• Trial end date: 2015-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Acute lower gastrointestinal dysfunction is a kind of much common complication which occurred in critically ill patients. Once it developed, enteral nutrition would be disturbed. In this study, investigators suppose that early application of a sufficient amount of pectin ahead of enteral nutrition, may promote recovery of acute lower gastrointestinal dysfunction in critically ill patients, and exert its good effect on early EN support.

Investigators designed this prospective randomized controlled trial to test and evaluates the effect whether EN feeding with or without a pectin start would be safe or with advanced clinical outcomes.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Xingwei Xu
• Treatments: Pectin

Criteria

Inclusion Criteria:：

• Adult ICU patients who were at least 18 years old if they were expected to require EN support within 36 hours after an unplanned ICU admission.

Exclusion Criteria:

• Could not be fed through enteral route,

• Had received EN in the past 2 months,

• Had a colectomy or jejunostomy in situ,

• Had severe colonic disease such as ulcerative colitis and Crohn's,

• Had pregnant,

• Had EN taboo crowd.