Peanuts and Glycemic Control

• Status: Completed
• Trial end date: 2019-12-20
• Target enrollment: 0
• Participant gender: All

Summary

A two-period randomized crossover study will be conducted to determine the effect of peanuts on glycemic control, and elucidate the role of the microbiome in glucose regulation, in individuals with impaired fasting glucose.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Penn State University
• Collaborator: The Peanut Institute

Criteria

Inclusion Criteria:

• Non-smoking

• Impaired fasting glucose at screening (≥ 100 mg/dL).

• BMI ≥20 and ≤40 kg/m2.

Exclusion Criteria:

• Diagnosed diabetes or fasting glucose >126 mg/dl

• Systolic blood pressure >160mmHg or diastolic blood pressure >100mmHg)

• Prescribed anti-hypertensive, lipid lowering or glucose lowering drugs

• Established cardiovascular disease, stroke, diabetes, liver, kidney or autoimmune disease or inflammatory conditions

• Use of supplements (psyllium, fish oil, soy lecithin, phytoestrogens) and botanicals and not willing to cease for the duration of the study

• Pregnancy or lactation

• Weight loss of >=10% of body weight within the 6 months prior to enrolling in the study

• Smoking or use of any tobacco products

• Allergy to test foods

• Consumption of >14 alcoholic drinks/week