Patients With Heart Failure ANd Type 2 Diabetes Treated With Placebo Or Metformin (PHANTOM) Pilot Study
Status:
Terminated
Trial end date:
2007-05-01
Target enrollment:
Participant gender:
Summary
To conduct a pilot study to evaluate the feasibility of a large randomized controlled trial
(RCT) of metformin in patients with heart failure and type 2 diabetes and to generate initial
morbidity and mortality estimates in this patient population. The primary hypothesis is that
subjects with heart failure and type 2 diabetes who receive metformin will have a significant
reduction in the combined endpoint of all-cause mortality and all-cause hospitalization as
compared to subjects who receive placebo therapy.