Pathways, Risk Factors, and mOleculeS to Prevent Early-onset Colorectal Tumors
Status:
NOT_YET_RECRUITING
Trial end date:
2027-08-31
Target enrollment:
Participant gender:
Summary
This research study is an open-label Phase 1 Exploratory/Pilot clinical trial to measure the effects of the incretin mimetic, tirzepatide, on tissue, urine, blood, and microbiome biomarkers associated with colorectal cancer risk and to understand the feasibility of this precision prevention trial approach for a future larger study.
Phase:
PHASE1
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborators:
Cancer Research UK National Cancer Institute (NCI)