Overview

Pathophysiology of Orthostatic Intolerance

Status:
Recruiting
Trial end date:
2025-12-01
Target enrollment:
0
Participant gender:
All
Summary
The purpose of this study is to describe the mechanism of orthostatic intolerance, relying on cardiovascular physiological studies. The syndrome is of undetermined etiology, but the syndrome causes impairment of a number of young adults, females more than males, with symptoms of tachycardia, fatigue, lightheadedness, palpitations, blurred vision, chest discomfort, difficulty concentrating, and dizziness with the upright posture. It is believed that many different pathophysiological processes can give rise to this disorder.
Phase:
N/A
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Satish R. Raj
Collaborator:
National Institutes of Health (NIH)
Treatments:
Propranolol
Criteria
Inclusion Criteria:

- Orthostatic intolerance

Exclusion Criteria:

- Inability or unwillingness to give informed consent