Patellar Tendinopathy - Effect of Training and Enhancement of the Collagen Synthesis by Insulin-like Growth Factor-I

• Status: Active, not recruiting
• Trial end date: 2020-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to test the hypothesis that stimulation of the synthesis of new structural tendon proteins combined with training improve the tendon structure in patients with chronic knee tendon pain.

• Phase: Early Phase 1
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bispebjerg Hospital
• Collaborator: The Danish Medical Research Council
• Treatments: Complement Factor I; Insulin; Insulin, Globin Zinc; Mitogens

Criteria

Inclusion Criteria:

• chronic patellar tendinopathy (> 3 months)

• anterior-posterior thickening of the tendon (1 mm compared to mid-tendon)

• hypo-echoic area with enhanced vascularization

Exclusion Criteria: injection

• corticosteroid injection within the last 12 months

• Knee operation

• Knee osteoarthritis

• Diabetes

• Smoking

• Body mass index >30