Partial Thromboplastin Time After 72 Hours of Antithrombotic Prophylaxis Using Unfractionated Heparin

• Status: Completed
• Trial end date: 2015-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study is designed to assess: the incidence of abnormal partial thromboplastin time in patients receiving unfractionated heparin (UFH) 5000 U 2 times a day versus 3 times a day 72 hours after administration of the first dose of heparin.

Hypothesis: The basic hypothesis of this study is that patients receiving UFH 5000 U subcutaneously 3 times a day will have a higher proportion of elevated partial thromboplastin time than patients receiving UFH 5000 U subcutaneously twice a day.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)
• Treatments: Calcium heparin; Heparin; Thromboplastin

Criteria

Inclusion Criteria:

• Patients undergoing an elective surgery by thoracoscopy requiring antithrombotic prophylaxis

• Anticipated duration of hospital stay of at least 3 days

Exclusion Criteria:

• Pre-existing coagulopathy

• Severe renal failure

• Known allergy to heparin

• History of heparin induced thrombocytopenia