Parathyroid Hormone (PTH) for Osteoporosis in Postmenopausal Women
Status:
Completed
Trial end date:
2009-12-01
Target enrollment:
Participant gender:
Summary
Parathyroid hormone (PTH) increases bone formation and thereby improves bone density and bone
strength in postmenopausal women with osteoporosis. However, prolonged PTH treatment
increases bone formation less and less over time. This study will test whether increasing the
daily dose of PTH sustains its ability to improve bone formation, and optional sub-studies
will test several potential reasons why PTH's effects on bone formation decline over time.
Phase:
Phase 2
Details
Lead Sponsor:
Massachusetts General Hospital
Collaborator:
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)