Overview

Parasitic Ulcer Treatment Trial Pilot

Status:
Recruiting
Trial end date:
2023-12-31
Target enrollment:
Participant gender:
Summary
This is a study of optimal treatments for acanthamoeba keratitis. In the first part of the study, participants will be randomized to chlorhexidine monotherapy or chlorhexidine plus povidone iodine. After four weeks of therapy, participants will be re-randomized to early corticosteroids, later corticosteroids, or placebo.
Phase:
Phase 2
Details
Lead Sponsor:
Francis I. Proctor Foundation
University of California, San Francisco
Collaborator:
Research to Prevent Blindness
Treatments:
Chlorhexidine
Chlorhexidine gluconate
Iodine
Methylprednisolone
Methylprednisolone Acetate
Methylprednisolone Hemisuccinate
Povidone
Povidone-Iodine
Prednisolone
Prednisolone acetate
Prednisolone hemisuccinate
Prednisolone phosphate