Overview
Parameters Associated With the Emergence of Resistance to Ciprofloxacin in Human Commensal Flora
Status:
Terminated
Terminated
Trial end date:
2005-07-01
2005-07-01
Target enrollment:
0
0
Participant gender:
All
All
Summary
Bacterial resistance to antibiotics has been a growing therapeutic problem since the late 1980s. Resistant strains of pathogenic bacteria can arise through initial selection of resistant strains in the commensal flora. The emergence of fluoroquinolone resistance in the commensal flora will be assessed in 48 healthy volunteers receiving variable doses of ciprofloxacin during 14 days. Emergence of resistance will be correlated to pharmacokinetic characteristics of ciprofloxacin.Phase:
N/AAccepts Healthy Volunteers?
Accepts Healthy VolunteersDetails
Lead Sponsor:
Assistance Publique - Hôpitaux de ParisTreatments:
Ciprofloxacin
Criteria
Inclusion Criteria:- healthy volunteers
Exclusion Criteria:
-