Paracetamol on Postoperative Nausea and Vomiting

• Status: Completed
• Trial end date: 2018-08-21
• Target enrollment: 0
• Participant gender: All

Summary

The drugs with both high potency and low side effects are preferred in the prevention of postoperative nausea and vomiting (PONV) which is a common problem. This prospective randomized study aimed to compare the efficacy of paracetamol on PONV in adults undergoing maxillofacial surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Adnan Menderes University; Aydin Adnan Menderes University
• Treatments: Acetaminophen; Metoclopramide

Criteria

Inclusion Criteria:

• ASA (the classification of the American Society of Anesthesiologists) physical status I-II

• Patients who scheduled for elective maxillofacial surgery under general anesthesia

Exclusion Criteria:

• Patients with a history of allergy to any of the study medications (opioid, general anesthetic agents or paracetamol)

• History of opioid use, hepatic or renal disease, coronary, psychotic and neurologic diseases

• Use of antiemetic, antihistaminic, analgesic or corticosteroid 24 hours (h) prior to surgery