Paracetamol and Neuropathic Pain

• Status: Unknown status
• Trial end date: 2019-09-30
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to evaluate the analgesic effect of paracetamol in patients suffering from pain with a peripheral neuropathic component in the presence of their usual treatment.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital, Clermont-Ferrand
• Treatments: Acetaminophen; Analgesics

Criteria

Inclusion Criteria:

• Patient aged 18 to 65 years,

• Patient suffering from chronic pain (for more than 3 months) with the characteristics of peripheral neuropathy and having pain assessed by a numerical scale ≥ 3 for one week, with at least 10 assessments completed,

• Patient agrees with not to take paracetamol, other than the treatment provided as part of the protocol, from inclusion to completion of the study,

• Acceptance to give a written consent.

Exclusion Criteria:

• Patient taking paracetamol daily,

• Patient with a contraindication to paracetamol administration (liver or renal failure, ...),

• Patient with a biological evaluation evaluated by the investigator as not compatible with the trial,

• Patient with a medical and/or surgical history evaluated by the investigator to be not compatible with the trial,

• Patient with drug treatments evaluated by the investigator to be not compatible with the trial,

• Pregnant or nursing woman,

• Patient with a cooperation and an understanding that does not allow for a strict compliance under the conditions set out in the protocol,

• Patient participating in another clinical trial, or being in an exclusion period, or having received a total amount of compensation exceeding 4500 euros over the 12 months preceding the start of the trial,

• Patient benefiting from a legal protection measure (curatorship, guardianship, protection of justice...),

• Patient not affiliated to the French Social Security system,

• Paracetamol intake during wash-out period.