Paracetamol and Metamizole With SPI-guided Anaesthesia for VRS

• Status: Unknown status
• Trial end date: 2020-01-10
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this randomized trial is to assess the efficacy of preemptive analgesia using paracetamol or metamizole or both of them under SPI-guided anaesthesia for vitreoretinal surgery (VRS), presence of PONV (postoperative nausea and vomiting) and oculocardiac reflex (OCR) and compare Numerical Rating Scale (NRS) with Surgical Pleth Index (SPI) for monitoring pain perception postoperatively.

Patients will receive general anaesthesia combined with either preemptive analgesia using preemptive intravenous infusion of 1,0 g of metamizol or preemptive intravenous infusion of 1,0 g of acetaminophen or both of them together.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Medical University of Silesia
• Collaborator: Silesian University of Medicine
• Treatments: Acetaminophen; Dipyrone

Criteria

Inclusion Criteria:

• written consent to participate in the study

• written consent to undergo general anaesthesia alone or combined with different techniques of pre-emptive analgesia and vitreoretinal surgery

Exclusion Criteria:

• history of allergy to local paracetamol or metamizole

• necessity of administration of vasoactive drugs influencing SPI monitoring

• pregnancy