Paracetamol Discontinuation in the Elderly After Long-term Consumption

• Status: Recruiting
• Trial end date: 2021-12-01
• Target enrollment: 0
• Participant gender: All

Summary

To investigate if long-term treatment of paracetamol can be discontinued without no worsening on pain, health-related quality-of-life and level of function compared to continuing paracetamol treatment in patients aged 65 years or more.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Hospital Bispebjerg and Frederiksberg
• Treatments: Acetaminophen

Criteria

Inclusion Criteria:

• 65 years or more

• Regular daily users of 3 to 4 grams of paracetamol for at least 6 months prior to enrollment

Exclusion Criteria:

• Malignant pain cf. their medical records

• Patients using other regular analgesics cf. indication on prescription

• Patients receiving paracetamol tablets with modified release or sustained release

• Patients in warfarin treatment

• Patients with terminal illnesses, cf. their medical records.

• Patients receiving dosages dispensed by their pharmacy

• Mini-Mental State Examination (MMSE) score less than 25

• Patients with or suspected to have COVID-19.