Palonosetron, Ondansetron, and Dexamethasone for Delayed Nausea and Vomiting in Autologous Transplant Patients
Status:
Completed
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
In this study, patients will receive ondansetron 8mg and dexamethasone 10mg intravenously 30
minutes prior to myeloablative preparative chemotherapy until the last day of chemotherapy.
On the final day of chemotherapy, palonosetron 0.25mg and dexamethasone 10mg will be
administered intravenously 30 minutes prior to the chemotherapy. If the chemotherapy regimen
is only 1 day of the chemotherapy then only palonosetron and dexamethasone will be
administered 30 minutes prior to chemotherapy. Dexamethasone 8mg once daily will be given
orally for 2 days following chemotherapy.