Palliative Treatment of Ulcerated Cutaneous Metastases: Trial Between Electrochemotherapy and Radiotherapy
Status:
Withdrawn
Trial end date:
2014-02-01
Target enrollment:
Participant gender:
Summary
By applying short electric pulses to cells, the cell membranes can become permeabilised
(electroporation). This can be used augment the effect of chemotherapy, by providing direct
access to the cell cytosol. For the drug bleomycin, the enhancement of effect is several
hundred fold, enabling once-only treatment. The investigators wish compare
electrochemotherapy with radiotherapy when treating ulcerated cutaneous metastases up to 5 cm
in diameter from any kind of histology.