Painless Local Infiltration Anesthesia

• Status: Completed
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to assess if a dilution with 1.4% sodium bicarbonate of a 2% mepivacaine+epinephrine solution, can be effective in reducing the pain associated with local infiltration anesthesia, during ambulatory phlebectomy procedures.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Campus Bio-Medico University
• Treatments: Anesthetics; Epinephrine; Epinephryl borate; Mepivacaine; Racepinephrine

Criteria

Inclusion Criteria:

• Patients undergoing ambulatory phlebectomy

Exclusion Criteria:

• Allergy to amide anesthetics

• Sinoatrial node disease or any degree of atrio-ventricular block

• Acute diseases

• Chronic kidney or liver disease

• Treatment with drugs that alter pain sensitivity (e.g. analgesics)

• Treatment with monoamine oxidase inhibitors or tricyclic antidepressants

• Major psychiatric disorders according to DSM IV-TR diagnostic criteria

• Alcohol abuse actual or recent as described in DSM IV-TR