Overview

Pain Outcomes Following Intralesional Corticosteroid Injections

Status:
Completed
Trial end date:
2019-09-01
Target enrollment:
0
Participant gender:
All
Summary
Corticosteroid therapy, including intralesional and topical applications, has many indications within the fields of Dermatology, Plastic Surgery, and Orthopedics. However, these injections can be quite painful, which leads many patients to discontinue treatment. Often, the injection involves a mixture of local anesthetic and corticosteroids despite a lack of evidence that the use of lidocaine improves pain. Due to the acidic pH, the lidocaine component of the injection can actually cause a significant burning sensation during the procedure. Lidocaine does not have anti-inflammatory properties and does not treat the underlying pathology. By including another medication, lidocaine also adds cost and risk to the procedure. The purpose of this study is to see if removing lidocaine from intralesional injections decreases the pain of injection.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Vanderbilt University Medical Center
Treatments:
Anesthetics
Anesthetics, Local
Lidocaine
Criteria
Inclusion Criteria:

- >12 years old presenting with an indication for intralesional steroid injection

Exclusion Criteria:

- Unconsentable

- Not a candidate for corticosteroid injection

- Contraindication to lidocaine