Pain Management After Cardiac Surgery - Opioids or NSAID

• Status: Completed
• Trial end date: 2013-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this randomized controlled study is to shed light on the analgesic properties and side-effect profile of an opiod-based regimen as opposed to an Ibuprofene based regimen.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Aalborg Universitetshospital; Aalborg University Hospital
• Treatments: Analgesics, Opioid; Oxycodone

Criteria

Inclusion Criteria:

• Cardiac surgery through median sternotomy

• Written consent

• Age over 18 years

Exclusion Criteria:

• Other forms of sternotomy (i.e. re-sternotomy or partial sternotomy)

• Preoperative creatinine over 110 µmol/L

• Preoperative use of opioids or NSAIDs in analgesic doses (aspirin in antithrombotic doses was accepted)

• Allergy to NSAIDs or opioids, and other contraindications to the used drugs

The postoperative exclusion criteria were:

• Staying more than one night at the intensive care unit

• Unacceptable side effects

• Exclusion at the patients request