PVP Iodine Effect on Post Debridement Bacteraemia

• Status: Completed
• Trial end date: 2013-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The study investigates the effect of supra- and subgingival rinsing of 10% PVP prior to ultrasonic debridement in patients with periodontitis (as compared to rinsing with water) in terms of post treatment bacteraemia.

Study design: Randomized split-mouth (cross-over) study on 20 generally healthy subjects.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Zurich
• Treatments: Cadexomer iodine; Iodine; Povidone-Iodine

Criteria

Inclusion Criteria:

• generally healthy, adult (≥ 18 years) patients with at least two periodontal pockets of ≥ 5 mm

Exclusion Criteria:

• Pregnancy

• Lactation

• Allergy on PVP-iodine

• anticoagulation (exception 100mg/d acetylsalicylic acid)

• high risc for endocarditis

• therapeutical radiation

• participation in other clinical studies

• cognitive impairment (patient unable to understand aim and conduction of the study