Objective:
This is a randomized controlled trial (RCT) in osteoporosis patients randomized to standard
parathyroid hormone (PTH) treatment alone or to standard PTH treatment and Whole-body
vibration (WBV). PTH is an effective but expensive anabolic treatment for osteoporosis. WBV
stimulates muscles and bones. A combined treatment might have synergistic or additive
beneficial effects on bone, reducing fracture risk making treatment more effective and
cost-effective. A beneficial effect on muscles and thereby falls risk of WBV may improve
fracture risk even further.
If the results of this pilot study are promising then a strong case can be made for a large
multi-centre RCT using strong endpoints including fractures and falls.
Phase:
N/A
Details
Lead Sponsor:
Odense University Hospital
Collaborators:
Copenhagen University Hospital, Denmark Hospital of South West Denmark Odense Patient Data Explorative Network OPEN - Odense Patient data Explorative Network Region of Southern Denmark Sygehus Lillebaelt University of Southern Denmark