PROLIFICA - West African Treatment Cohort for Hepatitis B
Status:
Completed
Trial end date:
2018-07-31
Target enrollment:
Participant gender:
Summary
The West African Treatment Cohort for Hepatitis B (WATCH) study is a component of the
European Commission Funded FP7 project PROLIFICA. It aims to evaluate a number of steps
required to successfully treat patients with chronic hepatitis B virus infection to prevent
cirrhosis and liver cancer. The first step is to determine whether screening for hepatitis B
using a point of care test is feasible and effective. The second is to monitor linkage from
screening into care. The third is to evaluate cheap non-invasive assessments to determine the
need for treatment. The fourth is to determine what proportion of patients meet treatment
eligibility criteria. The fifth step is to establish a treatment cohort which can be used to
measure adherence to therapy and avoidance of HBV related complications. A parallel untreated
cohort will be established to determine whether treatment criteria are relevant in this West
African setting by monitoring for complications of HBV infection.