Overview

PRISM Study-Pruritus Relief Through Itch Scratch Modulation

Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
To investigate the anti-pruritic efficacy and safety of Nalbuphine ER (NAL ER) tablets in Prurigo Nodularis. Subjects will be randomized to NAL ER (or matching placebo) with the primary endpoint evaluation at Week 14. During the open label extension, subjects who received NAL ER will continue on NAL ER and subjects who received placebo will crossover to NAL ER.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Trevi Therapeutics
Treatments:
Nalbuphine