PRGF Effectiveness for Myofascial Pain Treatment in Masticatory Muscles
Status:
Completed
Trial end date:
2019-08-25
Target enrollment:
Participant gender:
Summary
The investigators set up a randomized controlled clinical trial to evaluate the effectiveness
of plasma rich in growth factors (PRGF) injections into the masseter muscle trigger points
for myofascial pain treatment. The investigators also seek to compare PRGF injections
effectiveness with local anesthetic injections.
Dry needling and local anesthetics injections release trigger point by disrupting the
membranes of a tout band. However, the injected substance itself does not affect the
pathophysiological mechanism of the trigger point.
It is known that the platelets release growth factors who can enhance muscle regeneration
processes and moreover reduce chronic pain.
The investigators raised a hypothesis that PRGF injections into the trigger points in
masseter muscle can be an effective treatment method for the myofascial pain.