Overview PREVENTion of Clot in Orthopaedic Trauma Status: Recruiting Trial end date: 2022-02-01 Target enrollment: Participant gender: Summary The purpose of this study is to compare aspirin versus low-molecular weight heparin (LMWH) (Enoxaparin) as a thromboprophylaxis in patients who sustain a fracture. Phase: Phase 3 Details Lead Sponsor: Major Extremity Trauma Research ConsortiumCollaborator: Patient-Centered Outcomes Research InstituteTreatments: AspirinCalcium heparinDalteparinEnoxaparinHeparinHeparin, Low-Molecular-WeightTinzaparin