Overview

PPI Therapy Impact on GERD After Sleeve Gastrectomy

Status:
Not yet recruiting
Trial end date:
2022-09-01
Target enrollment:
0
Participant gender:
All
Summary
The trial would to try to establish: - The best post-operative PPI prescription protocol after Sleeve Gastrectomy - The impact of PPI therapy on postoperative peptic diseases (erosive gastropathies, ulcers, duodenitis, esophagitis and/or Barrett) - The impact of PPI therapy on post-operative GERD symptoms (assessed with the use of two standard tests: MRGE-HRQL and GERDQ
Phase:
Early Phase 1
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
University of Roma La Sapienza
Treatments:
Dexlansoprazole
Lansoprazole
Criteria
Inclusion Criteria:

- Patients candidates for primary SG

- Patients adhering to the follow-up protocol

- Age between 18 and 65 years

- No BMI limits

Exclusion Criteria:

- Gastric and/or esophageal diseases (routine preoperative endoscopy)

- Patients candidate for revisional bariatric surgery

- Chronic preoperative PPI therapy

- Using of PPI treatment for postoperative complications

- Conversion to open surgery

- Patients allergic to PPI

- Patients undergoing concomitant surgery

- Patients with hiatal hernia undergoing concomitant cruroplasty