Overview

PLATELET RICH FIBRIN COMBINED WITH 1.2% ATORVASTATIN FOR TREATMENT OF INTRABONY DEFECTS IN CHRONIC PERIODONTITIS

Status:
Completed

Trial end date:
2014-02-01

Target enrollment:
0

Participant gender:
All

Summary

Current study was designed to evaluate the combined efficacy of PRF and 1.2% ATV gel with open flap debridement (OFD) in treatment of intrabony defects in chronic periodontitis subjects.

Phase:

Phase 2

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Government Dental College and Research Institute, Bangalore

Treatments:

Atorvastatin
Atorvastatin Calcium

Criteria

Inclusion Criteria:

the presence of 3- wall IBD ≥3 mm deep (distance between alveolar crest and base of the
defect on an intraoral periapical radiograph [IOPA]) along with an interproximal probing
depth (PD) ≥5 mm after phase I therapy (scaling and root planing [SRP]) in asymptomatic
teeth.

Exclusion Criteria:

1) Agressive Periodontitis subjects; 2) Systemic conditions known to affect the periodontal
status; 3) medications known to affect the outcomes of periodontal therapy; 4)
Hematological disorders and insufficient platelet count (<200,000/mm3); 5)
pregnancy/lactation; and 6) Smoking and tobacco use in any form 7) Immunocompromised
individuals.