PK, PD and Safety Comparative Trial of Isosorbide Mononitrate Gel in Healthy Participants and With Anal Fissure
Status:
Withdrawn
Trial end date:
2017-11-01
Target enrollment:
Participant gender:
Summary
This is a Phase I trial to evaluate Pharmacokinetics, Pharmacodynamics and Safety of
Isosorbide Mononitrate gel for usage in participants with anal fissure and healthy
volunteers. Three doses will be used in patients with anal fissure (0.5%, 1.0% or 2.0%) and
healthy volunteers will receive 2.0% dose. All treatment will last 7 days.