PIB Versus CI Through a Popliteal Sciatic Nerve Catheter for Analgesia Following Major Ankle Surgery

• Status: Unknown status
• Trial end date: 2018-06-01
• Target enrollment: 0
• Participant gender: All

Summary

This is a clinical study to investigate and compare a new programmed intermittent bolus (PIB) delivery method for continuous popliteal sciatic nerve block for pain relief in patients undergoing major ankle surgery compared with the current practice of continuous local anesthetic infusion (CI).

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University Health Network, Toronto
• Treatments: Ropivacaine

Criteria

Inclusion Criteria:

• Inpatients having major foot and ankle surgery that will benefit from continuous popliteal sciatic nerve block with an indwelling catheter

• American Society Anesthesiologists (ASA) physical status I-III

• 18-85 years of age, inclusive

• 40-120 kg, inclusive

• 150 cm of height or greater

Exclusion Criteria:

• Patients who undergo iliac crest bone graft harvesting as part of their surgery

• Preexisting neurological deficits or peripheral neuropathy in the distribution of the sciatic nerve

• Local infection

• Contraindication to regional anesthesia e.g. bleeding diathesis, coagulopathy

• Chronic pain disorders

• History of use of over 30mg oxycodone or equivalent per day

• Allergy to local anesthetics

• History of significant psychiatric conditions that may affect patient assessment

• Pregnancy

• Inability to provide informed consent