PEriToneal Catheter Versus Repeated Paracentesis for Ascites in Cirrhosis
Status:
Terminated
Trial end date:
2019-05-15
Target enrollment:
Participant gender:
Summary
Insertion of a tunnelated peritoneal catheter (PleurX) allows repeated intermittent small
volume fluid drainage at home. The treatment may improve the management of ascites and have a
beneficial effect on the quality of life.
This study aims to evaluate the beneficial and harmful effects of the peritoneal catheter
(PleurX) versus repeated large volume paracentesis for patients with cirrhosis and diuretic
resistant ascites.
The trial is an investigator initiated, randomised, single blind, parallel arm, controlled
trial.
Tunnelated peritoneal (PleurX) catheter versus large volume paracentesis. All patients will
receive ciprofloxacin to prevent spontaneous bacterial peritonitis.
We will include 32 adult patients with cirrhosis Duration of trial 18 months. The total
duration of follow up is six months. The primary outcome is paracentesis free survival.