PETMRI for Chronic Pain from Spinal or Peripheral Nerve Origin
Status:
NOT_YET_RECRUITING
Trial end date:
2030-10-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to compare the uptake of \[18F\]FTC-146 in healthy volunteers to that of individuals suffering from chronic pain with Spinal or Peripheral Nerve Origin.
Primary Objectives:
A) To quantify the bio-distribution of \[18F\] FTC-146 uptake in subjects with Spinal or Peripheral Nerve Origin pain and compare it with healthy controls.
B) To determine whether painful schwannomas can be differentiated from non-painful schwannomas based on imaging.
Secondary Objectives:
A) To assess the reproducibility of \[18F\]FTC-146 PET imaging within the same healthy volunteer subjects using Test-Retest analysis.
B) To investigate whether post-treatment \[18F\]FTC-146 uptake differs from pre-treatment uptake and correlate the imaging with subject reported pain level after treatment