The primary aims of this study are to:
1. Quantify serotonin transporter (5-HTT) binding potential (BP) in vivo in bipolar
disorder patients (BPD) during a major depressive episode (MDE).
2. Assess the effect of lithium treatment of bipolar disorder on 5-HTT.
3. Assess the effect of lithium treatment of bipolar disorder on 5-HT1A BP.
4. Assess the effect of lamotrigine treatment of bipolar disorder on 5-HTT and 5-HT1A BP.
5. Assess the effect of lithium treatment of unipolar depression on 5-HTT BP.
Phase:
N/A
Details
Lead Sponsor:
Stony Brook University
Collaborators:
National Institute of Mental Health (NIMH) The Dana Foundation