PET Imaging of Radiolabeled Anti-HIV-1 Envelope Monoclonal Antibody (VRC01)
Status:
Recruiting
Trial end date:
2021-10-31
Target enrollment:
Participant gender:
Summary
This is a single center exploratory imaging study involving one intravenous microdose of
89Zr-DFO-VRC01 followed by whole-body PET-MR imaging in HIV infected individuals and healthy
volunteers. Imaging data will be obtained from up to four static PE-MR images in order to
determine dosimetry and temporal tissue uptake/tissue distribution of 89Zr-DFO-VRC01. This is
not a treatment study of the biological activity of 89Zr-DFO-VRC01 to impact HIV persistence.