The aim of this study is to explore the efficacy of 18F-FSPG in the detection of primary or
metastatic brain cancer lesions confirmed by a standard of truth, preferably histology. This
is a single center, open labelled, non-randomized study. A total of 30 subjects with brain
tumor or brain metastases will be enrolled. All different stages of malignancies will be
recruited, including those with different types of pathologies and grades, and newly
diagnosed or recurrent disease.