PET Imaging Study on Occupancy of Dopamine D2 Receptors and Genotypes After Bupropion Administration

• Status: Completed
• Trial end date: 2009-06-01
• Target enrollment: 0
• Participant gender: Male

Summary

Bupropion has different effects on D2 dopamine receptors according to genotype.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seoul National University Hospital
• Collaborators: Korea National Enterprise for Clinical Trials; Ministry of Health, Welfare and Family Affairs
• Treatments: Bupropion; Dopamine

Criteria

Inclusion Criteria:

• Active smoker (more than 10 cigarettes per day for the past 2 years)

Exclusion Criteria:

• Medical or psychiatric co-morbidity

• Hypersensitive to bupropion