Overview

PEG-Interferon Alfa-2b and Sorafenib in Treating Patients With Unresectable or Metastatic Kidney Cancer

Status:
Terminated
Trial end date:
2009-01-01
Target enrollment:
Participant gender:
Summary
RATIONALE: PEG-interferon alfa-2b may interfere with the growth of tumor cells. Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. It may also stop the growth of kidney cancer by blocking blood flow to the tumor. Giving PEG-interferon alfa-2b together with sorafenib may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of PEG-interferon alfa-2b and sorafenib in treating patients with unresectable or metastatic kidney cancer.
Phase:
Phase 1
Details
Lead Sponsor:
Thomas Olencki
Collaborator:
Schering-Plough
Treatments:
Interferon alpha-2
Interferon-alpha
Interferons
Niacinamide
Peginterferon alfa-2b
Sorafenib